Before visiting Boston and Tehran, let us just take a look at the news in the UK and USA during the past few days.
There is quite a lot of scepticism and criticism concerning the clear role of vitamin D in diminishing the impact of Covid-19 in the current pandemic in humankind. Is there a policy form the WHO downwards to suppress information about Vitamin D? We saw false information from the UK Health Secretary Matt Hancock on September 22nd, when he stated in Parliament that "Vitamin D does not appear to have any impact on reducing the incidence of Vitamin D".
On October 1st it was reported in the UK nation newspapers the The Times, The Mail and Metro that he admitted to this having been a false statement and that the research studies that he referred to did not exist.
There is a difference between the two statements:
"There is no evidence that vitamin D has an impact on Covid-19" and
"There is no evidence that vitamin D supplements have an impact on Covid-19".
The effect of vitamin D can be judged by the blood level of vitamin D and then associated with subsequent Covid-19 infection and deaths from it. It is beyond dispute, as judged by studies from Heidelberg, Bari, Chicago, and others, that low blood levels of vitamin D lead to an unfavourable outcome from Covid-19, possible death.
The benefit of taking a supplement is not quite the same, but the difference is pedantic. With the exception of Matt Hancock, most critics are careful to state that there is not evidence that vitamin D supplements are of benefit, rather than vitamin D.
How does someone living in northern Europe manage to become sufficient in vitamin D (blood level >30ng/ml, 75nmol/L) without taking a supplement? To organise a study of taking a vitamin D supplement takes much longer than testing blood levels.
But such a study has been undertaken in Spain and the result shows a dramatic benefit. It might be expected that all patients admitted to hospital on account of Covid-19 will now be given vitamin D as a routine. Is this happening? No-one really knows, BUT....
President Donald Trump was admitted to hospital on October 2nd on account of Covid-19, and the statement given by his physician Dr Sean Conley informs us that he is being given Vitamin D, among other treatments.
Clearly someone highly placed understands and acknowledges, perhaps in secret, the importance of vitamin D.
"Ich weiß, sie tranken heimlich Wein
Und predigten öffentlich Wasser"
For wine read "vitamin D". For water read "lockdown and vaccines"
However, there is more evidence available concerning the value of Vitamin D.
|Boston University medial Center|
For many years Boston has been leading research into vitamin D. The team is headed by Professor Michael Holick, whose activities and commitment are astounding. It was anticipated that good quality research would come out of his department during the pandemic of Covid-19 but of course research is not instantaneous and the research process takes some time.
The results of the research are now being published, and there are two papers of particular importance.
This study involved the health records of 191,779 US citizens who were found to be positive for Covid-19, and all of these persons had records of the results of blood levels of vitamin D during the previous 12 months. It was therefore possible to relate a pre-existing blood vitamin D level with subsequent Covid-19 infection.
The results can be summarised as the greater the blood level of vitamin D, the less is the chance of developing Covid-19. Details are shown in the graph.
We can see in this study three important criteria of proof of the causative role of vitamin D deficiency in Covid-19 infection, the criteria having been determined by Sir Austin Bradford Hill.
The first is association, there being a clear association between Covid-19 infection and low blood levels of vitamin D.
The second is temporality, as we see that low vitamin D levels pre-dated the Covid-19 infection.
The third is biological gradient, this being shown on the graph. There is a clear gradient of risk of Covid-19 with a varying blood level of vitamin D.
The conclusion is that a a good (sufficient) blood level of vitamin D will reduce by 50% the risk of Covid-19 infection.
The effect of blood vitamin D on serious or fatal Covid-19
|Sina Hospital, Tehran|
The second paper concerns the influence of vitamin D on the severity of Covid-19 infection. The study was undertaken in Tehran.
The title of this paper contains the conclusion.
The study was of 611 patients with Covid-19 in the Sina Hospital in Tehran.
Blood levels of vitamin D (as 25(OH)D) were determined on admission.
A blood level of 30ng/ml or more was regarded as "sufficient".
A blood level of less 30ng is therefore regarded as "insufficient".
The measure of severity of disease was based on the criteria of the US Centre for Disease Control and Prevention (CDC). The paper looks at Severe and Not Severe.
74% of the 235 patients had severe disease.
Blood vitamin levels (ng/ml) of the total patient group were:
We can see worse health, a higher incidence of the need for ICU admission, more severe illness, low oxygen levels, and loss of consciousness in those with the lower blood levels of vitamin D.
It is obviously a great advantage to have a good blood level of vitamin D (30ng/ml (75nmol/L) or greater) when admitted to hospital on account of Covid-19 infection.
In this study no-one under the age of 40 died.
16.3% of those aged 40 or older died.
Death was related to vitamin D status. 90.3% of those who died had a blood vitamin D level less than 30ng/ml (75nmol/L). Only 9.7% of those who died had blood level of 30ng/ml of greater.